sepsis
Conditions
Interventions
study group :no
Sponsors
Sir Run Run Shaw Hospital, Zhejiang Univerisity School of Medicine
Eligibility
Sex/Gender
Male
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Fulfillment of two of four criteria for the systemic inflammatory response syndrome and a systolic blood pressure no higher than 90 mm Hg (after a crystalloid-fluid challenge of 20 to 30 ml per kilogram of body weight over a 30-minute period) or a blood lactate concentration of 4 mmol per liter or more.
Exclusion criteria
Exclusion criteria: Aged of less than 18 years, pregnancy, or the presence of an acute cerebral vascular event, acute coronary syndrome, acute pulmonary edema, status asthmaticus, cardiac dysrhythmias (as a primary diagnosis), contraindication to central venous catheterization, active gastrointestinal hemorrhage, seizure, drug overdose, burn injury, trauma, a requirement for immediate surgery, uncured cancer (during chemotherapy), immunosuppression (because of organ transplantation or systemic disease), do-not-resuscitate status, or advanced directives restricting implementation. of the protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| temperature;heart rate;blood pressure;central venous pressure;lactate concentrations;Acute Physiology and Chronic Health Evaluation;SOFA score;Length of stay;All cause ICU mortality;Hospital cost; | — |
Countries
China
Contacts
Public ContactJian-cang Zhou
Outcome results
None listed