The Impact of CYP2D6*10 Polymorphism on Postoperative Patient-controlled Anesthesia Morphine Consumption in a Chinese Population

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-OCH-12002324

Enrollment

Unknown

Registered

2012-06-27

Start date

2012-03-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative analgesia

Interventions

Total:morphine

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Ages 18 to 70 years; 2. American Society of Anesthesiologists physical status of I or II; 3. Undergone abdominal surgery requiring general anesthesia; 4. Agreed to accept intravenous patient controlled analgesia (IV-PCA) with morphine for 72 hrs after the end of the operation.

Exclusion criteria

Exclusion criteria: 1. patients not receiving morphine after surgery; 2. patients on chronic pain medication; 3. patients with a history of a chronic pain syndrome; 4. patients with a body mass index of 32 kg/m2 or greater; 5. patients with significant systemic disease.

Design outcomes

Primary

Measure	Time frame
gene typy;	—

Countries

China

Contacts

Public ContactChunyu Song

scy-zw@163.com+86 18944614216

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026