Rectal cancer
Conditions
Interventions
A1:TME for rectal cancer with radiation and chemother
A2:Only TME for rectal cancer(East Asians)
B1:TME for rectal cancer with radiation and chemother
B2:TME for rectal cancer with radiation and chemother
Sponsors
Gastrointestinal Surgery Center of West China Hospital in Sichuan University
Eligibility
Sex/Gender
All
Age
16 Years to 95 Years
Inclusion criteria
Inclusion criteria: (1) patient who is considered to have rectal cancer by preoperative clinical or pathological diaginosis; (2) patient who has the operation completed with the sphincter-preserving surgery performed; (3) patients included by West China Hospital should be East Asians and those included by St. Paul's Hospital should be North Americans.
Exclusion criteria
Exclusion criteria: (1) patient who is found not with rectal cancer by the postoperative pathological diagnosis; (2) patient who has the operation completed with the permanent stoma performed eventually; (3) patient who cannot have the treatment completely as planned; (4) If the patients included by the research center do not meet the racial condition.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Source of population;distance from tumor to the anal margin;tumor location(upper/mid/distal);whether Neoadjuvant radiotherapy;dosage and period of neoadjuvant radiotherapy;operation type;Anastomosis(distance to the anus);anastomotic mode;whether perform temporary stoma;circumferential resection margin (CRM);complication-anastomotic leakage;whether adjuvant chemotherapy;dosage and period of adjuvant chemotherapy;whether neoadjuvant chemotherapy;dosage and period of neoadjuvant chemotherapy;T staging;N staging;M staging;preoperative CEA value;CEA value 6 months postoperation;CEA value12 months postoperation;whether local recurrence in the postoperative12 m;whether dead 12 months postoperation;whether dead 18 months postoperation;C30 score;C38 score;Wexner score; | — |
Secondary
| Measure | Time frame |
|---|---|
| gender;age;height;weight;Histological type;differentiation;operation time;intraoperative blood loss;ASA Grade;complication-anastomotic bleeding;complication-complete intestinal obstruction;complication-urinary retention;complication-gastric retention;complication-incision infection;postoperative hospital stay;total hospital stay; | — |
Countries
Canada
Contacts
Public ContactXiaodong Wang , Terry Phang
Outcome results
None listed