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The clinical study of application of probiotics in chidren with critical illness

The effects and mechanism of probiotics on immunitiy and ghrelin in children with critical illness

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCC-15007215
Enrollment
Unknown
Registered
2015-10-09
Start date
2014-02-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

critical illness in children

Interventions

probiotic group:probiotics

Sponsors

the people's hospital of Henan Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 4 Years

Inclusion criteria

Inclusion criteria: 1. the dangerous factors of developing into ALI; 2. acute onset; 3. arterial partial pressure of oxygen [P02] /oxygen inspired [FiO2]<=300mmHg; 4. no evidence of high pressure of left atrial or pulmonary artery wedge pressure (PAWP)<=18mmHg; 5. X-ray or CT of chest showed evident infiltration in both lungs, decrease of brightness, air bronchogram is positive partly.

Exclusion criteria

Exclusion criteria: The patients were excluded if they have congenital development malformation of heart andlung; genetic chromosomal disorders; congenital infections that were diagnosed after birth.

Design outcomes

Primary

MeasureTime frame
lung function;lung circulation;inflammation factors;T cell subset;cell surface receptor;intracellular RNA;—

Countries

China

Contacts

Public ContactWANG Yu
wangyugirl2004@126.com+86 15903992509

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026