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Validation of Khorana risk assessment model and the modified ones in identifying the high-risk group of chemotherapy-associated venous thromboembolism in lung cancer patients

Validation of Khorana risk assessment model and the modified ones in identifying the high-risk group of chemotherapy-associated venous thromboembolism in lung cancer patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCC-15006049
Enrollment
Unknown
Registered
2015-03-01
Start date
2015-04-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

venous thromboembolism

Interventions

None listed

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Histologically or cytologically confirmed diagnosis of Stage IIIB/IV lung cancer patients initiating chemotherapy; 2. Expected survival time was more than 6 months; 3. Karnofsky Performance Scale (KPS)>60%; 4. Heparin-based primary thromboprophylaxis was not used during chemotherapeutic cycles.

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiac, hepatic or renal dysfunction (cardiac function classification, by NYHA, grade III or IV; total bilirubin >=33umol/L; creatinine >=171umol/L or urine output <=500ml/24h); 2. Pregnant or lactating women; 3. Patients treated with high-dose glucocorticoids more than 30 days for other diseases; 4. Patients treated with immunosuppressive agents; 5. Patients with medical history of VTE or diagnosed with VTE in 48 hous of admission; 6. Patients unable to receive chemotherapy for some reasons; 7. Patients who can not provide prior informed consent or delayed informed consent; none of the above is desirable.

Design outcomes

Primary

MeasureTime frame
Complete blood count;Body mass index;D-dimer;Soluble P-selectin;Chemotherapy regimens;Pathological types of lung cancer;Venous thromboembolism;

Countries

China

Contacts

Public ContactChen Hong
417335669@qq.com+86 18680802072

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026