Breast Cancer
Conditions
Interventions
Group with neoadjuvant chemotherapy :Neoadjuvant chemotherapy and surgery
Sponsors
Southwest Hospital of Third Military University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Femaleage from 18 years old to 60 years, preoperative biopsy confirmed the diagnosis as invasive breast cancer; 2) Tumor size less than 3cmand there is no ulceration on the surface of the skin, and not invaded to the skin or muscle; 3) Clinical node-negative; 4) Patients without funtionnal failure of heart,lung,liver,kidney etc; 5) Patients without a history of radiotherapy to the breast and chest wall; 6) Signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1) Any part of the breast skin develop orange-peel sign; 2) Crater nipple or deflected nipple; 3) Breast cancer during pregnancy and lactation; 4) Distant metastasis; 5) Unwilling to undergo the surgery; 6) Researchers find that who"s not suitable for this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Circulating Tumor Cells;Operation situation;Infection;Nipple areola necrosis;Edema of the upper extremity;Capsular contracture; | — |
Secondary
| Measure | Time frame |
|---|---|
| Capsular contracture;Distant metastasis; | — |
Countries
China
Contacts
Public ContactFan Linjun
Southwest Hospital of Third Military University
Outcome results
None listed