Inflammatory bowel disease
Conditions
Sponsors
Nanfang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: IBD group Patients aged =18 with a diagnosis of Crohn's disease or ulcerative colitis defined by endoscopy, radiology and histology, and informed consent obtained; Healthy control: aged =18 and undergo colonoscopy for Health examination.
Exclusion criteria
Exclusion criteria: IBD group: Biological information database 1.significant hepatic, renal, endocrine, respiratory, neurological, cardiovascular disease, rheumatoid arthritis, autism or tumor as determined by the principal investigator; 2.current infection with an enteric pathogen, Intestinal amoebiasis, intestinal schistosomiasis, intestinal tuberculosis; 3.pregnancy or lactation; Sample collection (Beside the above mentioned items) 1.use of antibiotics within the last month; 2.consumption of any probiotic, prebiotic oryoghurt within the last month, clyster within the last month; 3.BMI>25; 4.participation in other experimental studies; 5.previous proctocolectomy; 6.short bowel syndrome; 7.imminent need for surgery. Healthy Control group: 1.histories of abdomen surgery and significant trauma; 2.pregnancy or lactation; 3.BMI>25; 4.use of antibiotics within the last month,consumption of any probiotic , prebiotic oryoghurt within the last month, clyster within the last month; 5.previously been diagnosed with IBD.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora diversity;CRP;ESR;TNF-a;Diet analysis; | — |
Countries
China
Contacts
Public ContactZhi Fachao
Nanfang Hospital of Southern Medical University
Outcome results
None listed