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Effects of Particulate Air Pollution on Ubiquitin-Proteasome System in Patients with Chronic Obstructive Pulmonary Disease: Role of Oxidative Stress, inflammation and protein oxidation

Effects of Particulate Air Pollution on Ubiquitin-Proteasome System in Patients with Chronic Obstructive Pulmonary Disease: Role of Oxidative Stress, inflammation and protein oxidation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCC-13004025
Enrollment
Unknown
Registered
2013-12-23
Start date
2014-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

NONE:NONE

Sponsors

Taiwan National Science Council
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: COPD Inclusion criteria: 1. Willing and signed informed consent; 2. males or females >=y/o and =y/o and >=80 y/o; 3. FEV1/FVC>= 75% and FEV1>= 80% predicted.

Exclusion criteria

Exclusion criteria: COPD Exclusion criteria: 1. known asthma, bronchiectasis, tuberculosis, pneumoconiosis, or other pulmonary diseases; 2. malignancy; 3. acute exacerbation or infection in 3 months. Normal non-smokers and healthy smokers: Exclusion criteria: 1. any acute infections, including upper airway infection, in 3 months; 2. Known major acute or chronic medial diseases.

Design outcomes

Primary

MeasureTime frame
COPD severity;—

Countries

China

Contacts

Public ContactHsiao-Chi Chuang
r92841005@gmail.com+886 970746972

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026