Aphasia
Conditions
Interventions
Mild cognitive impairment:Measurement of the scale
Aphasia:Measurement of the scale
Normal controls:Measurement of the scale
Sponsors
Department of Neurology, Nanfang Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aphasia patients (AP) (1) patients with stroke must be confirmed by CT and MRI; (2) patients must keep a stable mood and stay clear-minded; (3) patients must willingly cooperate for conditional visits; (4) the patients' aphasia needs to be identified and put into categories according to the Aphasia Battery of Chinese (ABC) and Benson; 2. Mild cognitive impairment (MCI)The Mayo Clinics criteria (Petersen et al., 1999; Petersen, 2004): (1) subjective cognitive complaint, preferably corroborated by a reliable informant; (2) objective cognitive impairment in the neuropsychological assessment; (3) preserved global intellectual function; (4) preserved or minimal impairment in activities of daily living; and (5) non-demented; 3. Normal controls (NC): (1) normal general physical status; (2) CDR = 0, independent in ADL; (3) no memory complaints; (4) the control group subjects match MCI patients on variables that were found to be predictive of the MoCA-BJs performance and additionally on gender.
Exclusion criteria
Exclusion criteria: 1. Aphasia patients (AP): (1) patients in coma, in unconscious state, and in vegetative state; (2) patients in serious condition, weak and not up for assessments, or those who unwillingly participate; (3) patients whose condition developed rapidly and acutely, deteriorated with signs of latest cerebral infarction or intracerebral hemorrhage, or internal organ dysfunction and failure; and (4) patients with subarachnoid hemorrhage, transient ischemic attack, or reversible ischemic neurological deficit; 2. Mild cognitive impairment (MCI): (1) metabolic conditions such as hypothyroidism or vitamin B12 or folic acid deficiencies; (2) psychiatric disorders such as schizophrenia or depression; (3) evident infarction or brain hemorrhaging as indicated by MR/CT imaging; or (4) Parkinsonian syndrome, epilepsy and other nervous system diseases; 3. Normal controls (NC)the subjects with kidney disease, thyroid gland disorders, drug abuse, or other diseases that may result in cognitive impairment were precluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The score of Non-linguistic Cognitive Assessment (NLCA) ;MoCA score; | — |
Countries
China
Contacts
Public ContactXiaojia LIU
Outcome results
None listed