bronchial asthma
Conditions
Interventions
actue asthma group:inhaled corticosteroid
Sponsors
The Affiliated Hospital of Guangdong Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients over 18 years of age with a history of physician-diagnosed asthma of at least 1-year duration, who were using inhaled ß2 agonist alone.Healthy subjects over 18 years of age with normal spirometry were recruited for the study as a negative control group. They were free of a history of asthma, reactive disease, and respiratory tract infection within 4 weeks prior to the study and from other significant illnesses known to affect FENO measurement. Both of asthma patients and healthy subjects were non-smokers and during the last year had not been passive smokers.
Exclusion criteria
Exclusion criteria: history of an acute asthma or respiratory tract infection during the previous month prior to enrolment; any active chronic cardiopulmonary disease other than asthma (including COPD); body mass index (BMI) was =25 kg/m2; on chronic immunosuppressive therapy; another acute condition; pregnant; could not provide informed consent or inability to perform spirometry and FENO measurements. Patients were dropped-out if any of the following adverse outcomes occurred during follow-up: recurrent acute exacerbation of asthma, initiation of mechanical ventilation or death.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lung function;FeNO;YKL-40; | — |
Countries
China
Contacts
Public ContactTianwen Lai
Outcome results
None listed