A Research of the Effects of Different Anaesthesia Medicine and Method and the Mechanism on Postoperative Cognitive Dysfunction After Non-cardiac Surgery in the Elderly

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-OCC-11001411

Enrollment

Unknown

Registered

2011-06-13

Start date

2010-10-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative cognitive dysfunction (POCD)

Interventions

Group I:Isoflurane

Group P:Propofol

Group S:Sevoflurane

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Male and female aged 65 to 80 years old; 2. Able and willing to provide signed informed consent; 3. Able to read and understand Chinese; 4. Undergo elective surgery (epigastrium); 5. American Anesthesia Association(ASA) I~III; 6. Body Mass Index (BMI) 18~30kg/m2.

Exclusion criteria

Exclusion criteria: 1. Cannot coordinate or present with language barrier; 2. With severe visual and auditory disorders; 3. With parkinson, alcohol abuse or durgs dependence problems; 4. Can not complete neuropsychological testing; 5. With other reasons that are not suitable for clinical trials.

Design outcomes

Primary

Measure	Time frame
Neuropsychological testing;Determination of blood sample;	—

Countries

China

Contacts

Public ContactYingjie GENG

gengyj123@163.com+86 13936265797

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026