Sepsis
Conditions
Interventions
Normal Control:none
Sponsors
Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns and Combined Injury
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. At least 18 years of age; 2. Suspected infection; 3. Two or more systemic inflammatory response syndrome (SIRS) criteria; 4. Temperature 38 degree C; 5. Heart rate 90 beats per minute; 6. Mechanical ventilation for acute respiratory process or respiratory rate > 20 breaths per minute or PaC02 12,000/mm3 OR 10% bands; 8. Refractory hypotension (a systolic blood pressure 4 mmol/L).
Exclusion criteria
Exclusion criteria: 1. Minors; 2. Patient under guardianship or trusteeship; 3. pregnant or lactating women; 4. diabetic; 5. cardiomyopathy known and/or treated or detect in admission; 6. electro-systolic process permanent or transitory; 7. neurological history or degenerative pathology; 8. chronic respiratory insufficiency; 9. Chronic renal insufficiency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum Pro-ET;serum Pro-ANP;Serum IL-6;serum CRP;serum TNF-a;serum PEDF;serum PCT; | — |
Countries
China
Contacts
Public ContactYuesheng Huang
Outcome results
None listed