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Study of cough sensitivity in patients with obstructive sleep apneahypopnea syndrome

Study of cough sensitivity in patients with obstructive sleep apneahypopnea syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCC-11001184
Enrollment
Unknown
Registered
2011-02-21
Start date
2010-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obstructive sleep apnea syndrome

Interventions

Snoring Group:Capsaicin cough sensitivity test
Normal Group:Capsaicin cough sensitivity test
OSA Group:Capsaicin cough sensitivity test

Sponsors

Shanghai Tongji Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. OSA Group: diagnosed obstructive sleep apneahypopnea syndrome by PSG; 2. Normal control: no OSA determined by PSG; 3. Snoring group: who snores,but have no OSA diagnosed by PSG.

Exclusion criteria

Exclusion criteria: 1. Pregnancy and lactation women; 2. Respiratory system diseases: occupational dust, poisonous and harmful gases exposure, Associated with asthma and chronic obstructive pulmonary disease, interstitial pneumonia, tuberculosis; 3. Other diseases: uncontrolled hypertension, serious cardiac arrhythmia, taking ACEI drugs or blockers; 4. Hepatic insufficiency, Renal insufficiency.

Design outcomes

Primary

MeasureTime frame
Serum inflammatory mediators;C2, C5, cell count of induced sputum , and cell classification;Sleep stages, the lowest oxygen saturation, and apnea hypoventilation index (AHI);—

Secondary

MeasureTime frame
Neck circumference, Body-mass index, Lung function, GERDQ score, Cough score;—

Countries

China

Contacts

Public ContactZhongmin Qiu
qiuzhongmin@yahoo.com.hk+86 021 66111286

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026