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The association of anticoagulant effects of warfarin with polymorphisms of genes in pharmacokinetic and pharmacodynamic pathway

The association of anticoagulant effects of warfarin with polymorphisms of genes in pharmacokinetic and pharmacodynamic pathway

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCC-10000778
Enrollment
Unknown
Registered
2009-12-02
Start date
2009-03-10
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart valve replacement

Interventions

Total:Warfarin and concomitant interacting medications, Genotypes

Sponsors

Guangdong General Hospital, Guangdong Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Chinese patients with heart valve replacement and with warfarin treatment

Exclusion criteria

Exclusion criteria: pregnancy

Design outcomes

Primary

MeasureTime frame
INR;

Secondary

MeasureTime frame
Bleeding and thromboembolic complication;

Countries

China

Contacts

Public ContactShuguang Lin
yuxycn@163.com+86 20 83827812-21180

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026