Dry age-related macular degeneration diseases
Conditions
Sponsors
Institute of zoology, chinese academy of sciences
Eligibility
Sex/Gender
All
Age
55 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 55-70 ys; 2. Diagnosed as atrophic age-related macular degeneration; 3. No CNV; 4. The BCVA of target eye will not be better than 20/400; 5. Diopter is greater than 8.00 D, axial length =28 mm; 6. Voluntary as test subjects, signed informed consent, regular follow-up will be effected according to the specified time.
Exclusion criteria
Exclusion criteria: 1. The macular atrophy caused by other disesaes in addition to AMD; 2. With history of other eye diseases or ocular traumas; 3. With history of intraocular surgery; 4. With serious systerm diseases, ALT/AST)> 1.5 or creatine > 1.3 mg/dL; 5. With any immunodeficiency disease; 6. Subject who are receiving immunosuppressive therapy; 7. Allergic to tacrolimus or Mycophenolate mofetil;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early treatment of diabetic retinopathy eye chart (ETDRs);Best corrected visual acuity;Fluorescein angiography;Optical coherent tomography (OCT);mutifocal electroretinogram (MFERG);Flash electroretinogram (FERG); HRA autofluorescence; | — |
Countries
China
Contacts
Public ContactZhou Qi
Outcome results
None listed