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The clinical trial of human mesenchymal stem cells therapy for severe ocular surface diseases

The clinical trial of human mesenchymal stem cells therapy for severe ocular surface diseases

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCB-15005972
Enrollment
Unknown
Registered
2014-10-14
Start date
2014-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe ocular surface diseases

Interventions

experimental group:subconjunctival injection of mesenchymal stem cells, futher more, intrastromal injection of mesenchymal stem cells

Sponsors

The eye insititute of Xiamen university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: severe ocular surface disease, such as chemical and thermal burn,severe corneal infection, Stevens-Johnson syndrome

Exclusion criteria

Exclusion criteria: 1. The chronic stage of severe ocular surface diseases, such as symblepharon,corneal conjunctivalization, corneal scarring; 2. Pregnancy patients.

Design outcomes

Primary

MeasureTime frame
vision;cornea fluorescein staining;slit lamp photography;the detection of inflammatory cytokines;—

Secondary

MeasureTime frame
ultrasound biomicroscopy(UBM);IOP(intraocular pressure);schirmer test;tear film break-up time;optical coherence tomography(OCT);impression cytology;—

Countries

China

Contacts

Public ContactWei Li
wei1018@xmu.edu.cn+86 15960215161

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026