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The clinical trial of human embryonic stem cell derived epithelial cells transplantation in the treatment of severe ocular surface diseases

The clinical trial of human embryonic stem cell derived epithelial cells transplantation in the treatment of severe ocular surface diseases

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-OCB-15005968
Enrollment
Unknown
Registered
2014-10-08
Start date
2015-10-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe Ocular Surface Disease

Interventions

Experimental group:Corneal-epithelium-like-cell transplantation

Sponsors

Eye Institute of Xiamen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Unilateral limbal stem cell deficiency; 2. Bilateral limbal stem cell deficiency.

Exclusion criteria

Exclusion criteria: 1. Active ocular surface inflammation; 2. Severe dry eye; 3. Progressive cicatricial disease; 4. Severe ocular surface squamous metaplasia; 5. Pregnant.

Design outcomes

Primary

MeasureTime frame
Vision;Corneal Fluorescein Staining;Slit Lamp Photography;—

Secondary

MeasureTime frame
Ultrasound Biomicroscopy(UBM);IOP(intraocular pressure);Schirmer Test;Break-up Time;Optical Coherence Tomography(OCT);Impression Cytology;—

Countries

China

Contacts

Public ContactWei Li
wei1018@gmail.com+86 0592-2183761

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026