The clinical observation of Diazocine and Butorphanol suppresse sufentanil-induced cough

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-17014201

Enrollment

Unknown

Registered

2017-12-28

Start date

2017-12-30

Completion date

Unknown

Last updated

2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dezocine:Given Dezocine 0.1mg/kg before induction of general anesthesia

Butorphanol:Given Butorphanol 0.02mg/kg before induction of general anesthesia

Saline:Given saline 5 ml before induction of general anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18~65 years old, ASA I-II; 2. No obvious abnormal cardiorespiratory function; 3. No obvious abnormal liver and kidney function; 4. There is no such thing as pneumothorax, aneurysm, cerebral hernia and other diseases that can cause serious consequences.

Exclusion criteria

Exclusion criteria: 1. Hypertension and taking angiotensin converting enzyme inhibitors; 2. Bronchial asthma or chronic obstructive pulmonary disease;There are upper respiratory tract infections and coughs in the last two weeks; 3. Obesity, liver, renal dysfunction; 4. The induction period, such as ephedrine, atropine and tracheal intubation time of more than 30s or repeatedly intubation; 5. No informed consent was signed.

Design outcomes

Primary

Measure	Time frame
cough times;	—

Secondary

Measure	Time frame
The blood pressure;Heart rate;Pulse oxygen saturation;	—

Countries

China

Contacts

Public ContactJinghui Shi

The First Affiliated Hospital of Harbin Medical University

jinghui-shi@hotmail.com+86 15114641234

Outcome results