Chronic kidney disease
Conditions
Interventions
Control group:Basic treatment
Bailing capsule low-dose group:Bailing capsule: 3g /d
Bailing capsule high dose group:Bailing capsule: 9g /d
Sponsors
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Aged 18 to 70 years old; (2) CKD patients eGFR 15 to 60ml/min.1.73m2. (3) sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) poor compliance, can not be followed up on schedule; (2) are participating in interventional clinical trials; (3) patients with acute kidney injury (AKI), that is, serum creatinine increased within 48 hours = 0.3mg/dl; or within 7 days serum creatinine more than 1.5 times the baseline value; or urine output <0.5ml / kg / h greater than 6 hours. (4) Previously received organ or bone marrow transplantation; (5) There are active or metastatic tumors within 2 years before screening; (6) Expected life expectancy <6 months; (7) Severe cardiac insufficiency (NYHA class III or IV heart failure, that is, with underlying heart disease, body Force activities were significantly limited, less than normal physical activity or even resting state can be tired, palpitations, asthma Or angina pectoris); (8) HIV infection or AIDS; (9) there is dementia or other mental disorders, physical activity is limited, severe visual impairment can not match complete the assessment; (10) patients undergoing immunosuppressive therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glomerular filtration rate;24-hour urine protein quantitation; | — |
Countries
China
Contacts
Public ContactYueyi Deng
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed