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Effect of endometrial injury on MMPs and its inhibitor and pregnancy outcome before frozen-thawed embryo transfer

Effect of endometrial injury on MMPs and its inhibitor and pregnancy outcome before frozen-thawed embryo transfer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-17014013
Enrollment
Unknown
Registered
2017-12-18
Start date
2018-03-01
Completion date
Unknown
Last updated
2018-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reproductive Medicine

Interventions

injury group:endometrial injury in menstrual phase
control group:non-injury in menstrual phase

Sponsors

HeFei Maternity and Child Health Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: women indicated for FET, at least had one or more good quality frozen embryos, the normal form of uterine cavity, no history of pelvic surgery, no transfer difficult history and aged less than 42 years.

Exclusion criteria

Exclusion criteria: intrauterine abnormality(severe adhesions,uterine polyp,submucosal fibroma), hydrosalpinx and endometriosis.

Design outcomes

Primary

MeasureTime frame
live birth rate;clinical pregnancy rate;imlantation rate;MMP-2;MMP-9;TIMP-2;TIMP-1;—

Secondary

MeasureTime frame
Miscarriage rate;Multiple pregnancy rate;Ectopic rate;—

Countries

China

Contacts

Public ContactTang Zhixia

HeFei Maternity and Child Health Hospital

tzx1999@163.com+86 15955164659

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026