important organ damage
Conditions
Interventions
two:The intravenous injection of DEX 1.0u g/kg in the first 10min intravenously, and the intravenous pump was used with DEX 0.6u g/(kg - h) until the end of the operation
Sponsors
Nanjing DrumTower Hospital Anesthesiology Department
Eligibility
Sex/Gender
All
Age
53 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) patients with a single pulmonary ventilation method for esophageal cancer radical surgery; (2) male, or non-pregnant, non-lactating women; (3) =65.
Exclusion criteria
Exclusion criteria: (1) patients who had been treated with DEX and/or ulinastatin 1 month before surgery; (2) the patient has an important organ disease or infection that is difficult to control; (3) there is a clear history of allergic diseases or an allergic reaction to the study of drugs; (4) spiritual disease; (5) patients with obvious lung disease before surgery; (6) patients with obvious cardiac organic disease before surgery; (7) the patient has serious medical risk factors, including any major organ function status, and the researchers believe that if the study is accepted, it may affect the life safety of the subject.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NSE;S100ß;MMSE;BMP;cTnI; | — |
Countries
China
Contacts
Public ContactZheyan Wang
Nanjing DrumTower Hospital Anesthesiology Department
Outcome results
None listed