gastric cancer
Conditions
Interventions
CAPOX group:Oxaliplatin 130mg / m2, intravenous infusion of the first day
capecitabine 1000mg / m2, orally, 2 times / day, 1-14 days, 21 days for a cycle. A total of 8 cycles.
SOX group:Oxaliplatin 130mg / m2, intravenous infusion of the first day
Tegafur 60mg/time, oral, two time a day in day 1 to day 14, 21 days a cycle, total 8 cycles.
Sponsors
Tianjin Medical University General Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Histologically proven adenocarcinoma of the stomach; 2. Clinical stage IB-III; 3. No bulky lymph node metastasis is detected by abdominal CT; 4. Aged 20 to 80 years; 5. No previous treatment with chemotherapy or radiation therapy for any tumors; 6. No previous surgery for the present disease; 7. No obvious contraindications for laparoscopic operation; 8. R0 removal can be achieved by laparoscopy.
Exclusion criteria
Exclusion criteria: 1. Abdominal surgery history; 2. Gastrointestinal surgery history; 3. Surgery did not reach the range of D2 lymph node dissection; 4. Patients who have participated in other clinical studies in the last 4 weeks; 5. Researchers think there are other cases that are not suitable for participating in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3 year overall survival;3 year progression free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life;adverse reactions; | — |
Countries
China
Contacts
Public ContactWeihua Fu
Tianjin Medical University General Hospital
Outcome results
None listed