orthopedic operation surgery
Conditions
Interventions
control group:no tranexamic acid
intermittent administration of tranexamic acid:intermittent administration of tranexamic acid
continuous administration of tranexamic acid:continuous administration of tranexamic acid
Sponsors
Beijing Jishuitan Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Aged >18 years old, ASA I-III underwent internal fixation of spine, acetabular fractures, femoral shaft fracture, pelvic fracture, humeral shaft fracture and proximal humeral fractures as well as revision of total hip arthroplasty and total hip replacement of high congenital dislocation of the hip
Exclusion criteria
Exclusion criteria: 1. cardiac, pulmonary, renal and hepatic disorders; 2. long-term administration of NSAIDs; 3. coagulation disorders, and platelet count; 4. history of deep vein thrombosis (DVT) or pulmonary embolism; 5. hematological disorder, some peripheral vascular disease, such as K-T syndrome, and anaemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intraoperative blood loss;autologous blood transfusion;DVT;allogeneic blood transfusion;coagulation function;TEG;platelet function; | — |
Countries
China
Contacts
Public ContactGeng Wang
Beijing Jishuitan Hospital
Outcome results
None listed