chronic renal failure
Conditions
Interventions
Experimental group:Folic Acid Tablets 15 mg/d+ vitamin B6 tablets 60mg/d+ vitamin B12 tablets 0.5mg/d
Control group:placebo
Sponsors
The Third Affiliated Hospital, Sun Yat-Sen University, Yuedong Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Serum creatinine levels ranged from 1.5 to 5 mg/dl (133 to 442 mol/L) and creatinine clearance ranged from 20 to 70 ml/1.73 m2, and within three months the change was less than 30%. No urinary tract infection or obvious heart failure (New York Heart Association class III or IV]), all patients were given drug eluting for 6 weeks, and stopped taking folic acid, vitamin B6 and vitamin B12 drugs.;Inclusion criteria: Serum creatinine levels ranged from 1.5 to 5 mg/dl (133 to 442 mol/L) and creatinine clearance ranged from 20 to 70 ml/1.73 m2, and within three months the change was less than 30%. No urinary tract infection or obvious heart failure (New York Heart Association class III or IV]), all patients were given drug eluting for 6 weeks, and stopped taking folic acid, vitamin B6 and vitamin B12 drugs.;Inclusion criteria: Serum creatinine levels ranged from 1.5 to 5 mg/dl (133 to 442 mol/L) and creatinine clearance ranged from 20 to 70 ml/1.73 m2, and within three months the change was less than 30%. No urinary tract infection or obvious heart failure (New York Heart Association class III or IV]), all patients were given drug eluting for 6 weeks, and stopped taking folic acid, vitamin B6 and vitamin B12 drugs.;Inclusion criteria: Serum creatinine levels ranged from 1.5 to 5 mg/dl (133 to 442 mol/L) and creatinine clearance ranged from 20 to 70 ml/1.73 m2, and within three months the change was less than 30%. No urinary tract infection or obvious heart failure (New York Heart Association class III or IV]), all patients were given drug eluting for 6 weeks, and stopped taking folic acid, vitamin B6 and vitamin B12 drugs.;Inclusion criteria: Serum creatinine levels ranged from 1.5 to 5 mg/dl (133 to 442 mol/L) and creatinine clearance ranged from 20 to 70 ml/1.73 m2, and within three months the change was less than 30%. No urinary tract infection or obvious heart failure (New York Heart Association class III or IV]), all patients were given drug eluting for 6 weeks, and stopped taking folic acid, vitamin B6 and vitamin B12 drugs.
Exclusion criteria
Exclusion criteria: (1) have received renal replacement therapy; (2) selected within 1 months before the occurrence of infection; (3) acute cardiovascular events in 1 months before; (4) the use of hormone or immunosuppressant; (5) with malignant tumor, mental illness or pregnancy.;Exclusion criteria: (1) have received renal replacement therapy; (2) selected within 1 months before the occurrence of infection; (3) acute cardiovascular events in 1 months before; (4) the use of hormone or immunosuppressant; (5) with malignant tumor, mental illness or pregnancy.;Exclusion criteria: (1) have received renal replacement therapy; (2) selected within 1 months before the occurrence of infection; (3) acute cardiovascular events in 1 months before; (4) the use of hormone or immunosuppressant; (5) with malignant tumor, mental illness or pregnancy.;Exclusion criteria: (1) have received renal replacement therapy; (2) selected within 1 months before the occurrence of infection; (3) acute cardiovascular events in 1 months before; (4) the use of hormone or immunosuppressant; (5) with malignant tumor, mental illness or pregnancy.;Exclusion criteria: (1) have received renal replacement therapy; (2) selected within 1 months before the occurrence of infection; (3) acute cardiovascular events in 1 months before; (4) the use of hormone or immunosuppressant; (5) with malignant tumor, mental illness or pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| homocysteine;left ventricular hypertrophy; | — |
Countries
China
Contacts
Public ContactHongyong LIU;Hongyong LIU;Hongyong LIU;Hongyong LIU;Hongyong LIU ;;;;
The Third Affiliated Hospital, Sun Yat-Sen University, Yuedong Hospital;The Third Affiliated Hospital, Sun Yat-Sen University, Yuedong Hospital;The Third Affiliated Hospital, Sun Yat-Sen University, Yuedong Hospital;The Third Affiliated Hospital, Sun Yat-Sen University, Yuedong Hospital;The Third Affiliated Hospital, Sun Yat-Sen University, Yuedong Hospital
Outcome results
None listed