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Effect of early heart rate control by ivabradine on left ventricular remodeling after primary percutaneous coronary intervention in patients with acute ST segment elevation myocardial infarction

Effect of early heart rate control by ivabradine on left ventricular remodeling after primary percutaneous coronary intervention in patients with acute ST segment elevation myocardial infarction

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-17013125
Enrollment
Unknown
Registered
2017-10-26
Start date
2017-12-01
Completion date
Unknown
Last updated
2017-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction

Interventions

treatment group:ivabradine

Sponsors

Shenzhen Sun Yat-sen Cardiovascular Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) the diagnosis of STEMI was defined according to the global definition of acute myocardial infarction, and the ECG showed ST segment elevation in 2 adjacent leads or new left bundle branch block; 2) successful emergency PCI, infarct related vascular TIMI level 3; 3) patients 12 hours after PCI treatment, sinus rhythm, heart rate was=80 beats per minute. 4) within 3 months,there is no history of the use of ivabradine.;Inclusion criteria: 1) the diagnosis of STEMI was defined according to the global definition of acute myocardial infarction, and the ECG showed ST segment elevation in 2 adjacent leads or new left bundle branch block; 2) successful emergency PCI, infarct related vascular TIMI level 3; 3) patients 12 hours after PCI treatment, sinus rhythm, heart rate was=80 beats per minute. 4) within 3 months,there is no history of the use of ivabradine.;Inclusion criteria: 1) the diagnosis of STEMI was defined according to the global definition of acute myocardial infarction, and the ECG showed ST segment elevation in 2 adjacent leads or new left bundle branch block; 2) successful emergency PCI, infarct related vascular TIMI level 3; 3) patients 12 hours after PCI treatment, sinus rhythm, heart rate was=80 beats per minute. 4) within 3 months,there is no history of the use of ivabradine.;Inclusion criteria: 1) the diagnosis of STEMI was defined according to the global definition of acute myocardial infarction, and the ECG showed ST segment elevation in 2 adjacent leads or new left bundle branch block; 2) successful emergency PCI, infarct related vascular TIMI level 3; 3) patients 12 hours after PCI treatment, sinus rhythm, heart rate was=80 beats per minute. 4) within 3 months,there is no history of the use of ivabradine.;Inclusion criteria: 1) the diagnosis of STEMI was defined according to the global definition of acute myocardial infarction, and the ECG showed ST segment elevation in 2 adjacent leads or new left bundle branch block; 2) successful emergency PCI, infarct related vascular TIMI level 3; 3) patients 12 hours after PCI treatment, sinus rhythm, heart rate was=80 beats per minute. 4) within 3 months,there is no history of the use of ivabradine.

Exclusion criteria

Exclusion criteria: 1) PCI treatment is not successful, the infarct related artery blood TIMI level=2; 2) hemodynamic instability or acute pulmonary edema; 3) non-sinus rhythm; 4) 12 hours after PCI, the heart rate is <80 / min.;Exclusion criteria: 1) PCI treatment is not successful, the infarct related artery blood TIMI level=2; 2) hemodynamic instability or acute pulmonary edema; 3) non-sinus rhythm; 4) 12 hours after PCI, the heart rate is <80 / min.;Exclusion criteria: 1) PCI treatment is not successful, the infarct related artery blood TIMI level=2; 2) hemodynamic instability or acute pulmonary edema; 3) non-sinus rhythm; 4) 12 hours after PCI, the heart rate is <80 / min.;Exclusion criteria: 1) PCI treatment is not successful, the infarct related artery blood TIMI level=2; 2) hemodynamic instability or acute pulmonary edema; 3) non-sinus rhythm; 4) 12 hours after PCI, the heart rate is <80 / min.;Exclusion criteria: 1) PCI treatment is not successful, the infarct related artery blood TIMI level=2; 2) hemodynamic instability or acute pulmonary edema; 3) non-sinus rhythm; 4) 12 hours after PCI, the heart rate is <80 / min.

Design outcomes

Primary

MeasureTime frame
LVEDV;LVEDV;LVESV;LVM;LVEF;

Countries

China

Contacts

Public ContactYan Xu;Yan Xu;Yan Xu;Yan Xu;Yan Xu ;;;;

Shenzhen Sun Yat-sen Cardiovascular Hospital;Shenzhen Sun Yat-sen Cardiovascular Hospital;Shenzhen Sun Yat-sen Cardiovascular Hospital;Shenzhen Sun Yat-sen Cardiovascular Hospital;Shenzhen Sun Yat-sen Cardiovascular Hospital

szxuxu1967@hotmail.com;szxuxu1967@hotmail.com;szxuxu1967@hotmail.com;szxuxu1967@hotmail.com;szxuxu1967@hotmail.com+86 15813833635;+86 15813833635;+86 15813833635;+86 15813833635;+86 15813833635

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026