lumbar spinal stenosis or lumbar disc herniation
Conditions
Interventions
Cocktail Group:cocktail analgesic injection and postoperative intravenous patient-controlled analgesia
Control Group:normal saline injection and postoperative intravenous patient-controlled analgesia
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Aged between 18 and 70 years; 2) On the surgical waiting list for primary lumbar spinal fusion surgery at PUMCH; 3) Diagnosed with lumbar spinal stenosis or lumbar disc herniation; 4) American Society of Anesthesiologists (ASA) physical status I~II; 5) Understand and comply with the study protocol.;Inclusion criteria: 1) Aged between 18 and 70 years; 2) On the surgical waiting list for primary lumbar spinal fusion surgery at PUMCH; 3) Diagnosed with lumbar spinal stenosis or lumbar disc herniation; 4) American Society of Anesthesiologists (ASA) physical status I~II; 5) Understand and comply with the study protocol.;Inclusion criteria: 1) Aged between 18 and 70 years; 2) On the surgical waiting list for primary lumbar spinal fusion surgery at PUMCH; 3) Diagnosed with lumbar spinal stenosis or lumbar disc herniation; 4) American Society of Anesthesiologists (ASA) physical status I~II; 5) Understand and comply with the study protocol.;Inclusion criteria: 1) Aged between 18 and 70 years; 2) On the surgical waiting list for primary lumbar spinal fusion surgery at PUMCH; 3) Diagnosed with lumbar spinal stenosis or lumbar disc herniation; 4) American Society of Anesthesiologists (ASA) physical status I~II; 5) Understand and comply with the study protocol.;Inclusion criteria: 1) Aged between 18 and 70 years; 2) On the surgical waiting list for primary lumbar spinal fusion surgery at PUMCH; 3) Diagnosed with lumbar spinal stenosis or lumbar disc herniation; 4) American Society of Anesthesiologists (ASA) physical status I~II; 5) Understand and comply with the study protocol.
Exclusion criteria
Exclusion criteria: 1) History of hypersensitivity to parecoxib, ropivacaine, diprospan, fentanyl or sulfonamide; 2) Serious allergic reaction to any other drugs; 3) Gastrointestinal hemorrhage or ulcer; 4) Severe hepatic, renal, or cardiovascular dysfunction; 5) Perioperative period of coronary artery bypass surgery; 6) Pregnant, lactating or probably pregnant; 7) Revision surgery or surgery for neoplastic disease; 8) Inability to provide informed consent due to mental incompetence (e.g., intellectual disability, dementia); 9) Drug or alcohol abuse; 10) Limited Chinese language fluency.;Exclusion criteria: 1) History of hypersensitivity to parecoxib, ropivacaine, diprospan, fentanyl or sulfonamide; 2) Serious allergic reaction to any other drugs; 3) Gastrointestinal hemorrhage or ulcer; 4) Severe hepatic, renal, or cardiovascular dysfunction; 5) Perioperative period of coronary artery bypass surgery; 6) Pregnant, lactating or probably pregnant; 7) Revision surgery or surgery for neoplastic disease; 8) Inability to provide informed consent due to mental incompetence (e.g., intellectual disability, dementia); 9) Drug or alcohol abuse; 10) Limited Chinese language fluency.;Exclusion criteria: 1) History of hypersensitivity to parecoxib, ropivacaine, diprospan, fentanyl or sulfonamide; 2) Serious allergic reaction to any other drugs; 3) Gastrointestinal hemorrhage or ulcer; 4) Severe hepatic, renal, or cardiovascular dysfunction; 5) Perioperative period of coronary artery bypass surgery; 6) Pregnant, lactating or probably pregnant; 7) Revision surgery or surgery for neoplastic disease; 8) Inability to provide informed consent due to mental incompetence (e.g., intellectual disability, dementia); 9) Drug or alcohol abuse; 10) Limited Chinese language fluency.;Exclusion criteria: 1) History of hypersensitivity to parecoxib, ropivacaine, diprospan, fentanyl or sulfonamide; 2) Serious allergic reaction to any other drugs; 3) Gastrointestinal hemorrhage or ulcer; 4) Severe hepatic, renal, or cardiovascular dysfunction; 5) Perioperative period of coronary artery bypass surgery; 6) Pregnant, lactating or probably pregnant; 7) Revision surgery or surgery for neoplastic disease; 8) Inability to provide informed consent due to mental incompetence (e.g., intellectual disability, dementia); 9) Drug or alcohol abuse; 10) Limited Chinese language fluency.;Exclusion criteria: 1) History of hypersensitivity to parecoxib, ropivacaine, diprospan, fentanyl or sulfonamide; 2) Serious allergic reaction to any other drugs; 3) Gastrointestinal hemorrhage or ulcer; 4) Severe hepatic, renal, or cardiovascular dysfunction; 5) Perioperative period of coronary artery bypass surgery; 6) Pregnant, lactating or probably pregnant; 7) Revision surgery or surgery for neoplastic disease; 8) Inability to provide informed consent due to mental incompetence (e.g., intellectual disability, dementia); 9) Drug or alcohol abuse; 10) Limited Chinese language fluency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sufentanil consumption;Time to first use of IV-PCA;Rescue analgesia consumption; | — |
Countries
China
Contacts
Public ContactShugang Li;Shugang Li;Shugang Li;Shugang Li;Shugang Li ;;;;
Peking Union Medical College Hospital;Peking Union Medical College Hospital;Peking Union Medical College Hospital;Peking Union Medical College Hospital;Peking Union Medical College Hospital
Outcome results
None listed