Osteoporosis in Menopausal Women
Conditions
Interventions
group A:erzhi pill
groupB:Caltrate
Sponsors
Second Affiliated Hospital of Tianjin University of TCM
Eligibility
Sex/Gender
Female
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. femal aged 45 to 65 years old,during the period of perimenopause or early postmenopause (less than 5years); 2. Osteoporosis was diagnosed; 3. liver and kindey yin-deficiency; 4. informed consent form has been signed.
Exclusion criteria
Exclusion criteria: 1. Secondary Osteoporosis or Idiopathic osteoporosis; 2. Surgical menopause; 3. Known hypersensitivity to the investigational drugs or their ingredients; 4. Patients with diseases as follows: malignant tumor; hyperthyroidism, hypothyroidism, uncontrolled diabetes; obesity (body mass index greater than 30); neurasthenia, psychiatric disorders, migraine headache; hematopoietic system diseaseautoimmune system diseases; Fungal or bacterial vaginal infections; Hypercalcemia; 5. Abnormal liver function or abnormal renal function; 6. The participants used the same treatment of traditional Chinese medicine in the previous 4 weeks. Use Estrogen or estrogen/progesterone drugs through vaginal or percutaneous or oral style in the previous 8 weeks. Take progesterone implants and a separate injection of estrogen therapy in the previous 3 months, Take estrogen pills or progesterone injection in the previous 6 months; 7. patients with severe osteoporosis and fracture,or deformity, loss of labor force.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Menopause-specific quality-of-life (MENQOL);bone density; | — |
Secondary
| Measure | Time frame |
|---|---|
| Osteoporosis symptom rating scale;FSH, E2, Testosterone;Blood calcium,Blood phosphorus ,ALP; | — |
Countries
China
Contacts
Public ContactGao Xiumei
Second Affiliated Hospital of Tianjin University of TCM
Outcome results
None listed