Menopausal Hypertension
Conditions
Interventions
group A:hypotensor+erzhi pill
group B:hypotensor+placebo
Sponsors
Second Affiliated Hospital of Tianjin University of TCM
Eligibility
Sex/Gender
Female
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. femal aged 45 to 65years old, during the period of perimenopause or early postmenopause (less than 5years); 2. patients with hypertension grade 1 or 2; 3. diagnosed hypertension during menopause; 4. liver and kindey yin-deficiency; 5. informed consent form has been signed.
Exclusion criteria
Exclusion criteria: 1. secondary hypertension; 2. Known hypersensitivity to the investigational drugs or their ingredients; 3. Patients with diseases as follows:malignant tumor; hyperthyroidism,hypothyroidism, uncontrolled diabetes; obesity (body mass index greater than 30); neurasthenia, psychiatric disorders, migraine headache;hematopoietic system diseaseautoimmune system diseases; Fungal or bacterial vaginal infections; 4. Surgical menopause; 5. Abnormal liver function or abnormal renal function; 6. The participants used the same treatment of traditional Chinese medicine in the previous 4 weeks. Use Estrogen or estrogen/progesterone drugs through vaginal or percutaneous or oral style in the previous 8 weeks. Take progesterone implants and a separate injection of estrogen therapy in the previous 3 months, Take estrogen pills or progesterone injection in the previous 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24hour ambulatory blood pressure;Menopause-specific quality-of-life (MENQOL); | — |
Secondary
| Measure | Time frame |
|---|---|
| FSH, E2, Testosterone;Serum lipids (total cholesterol, HDL and LDL chole;count numbers (EPCs, CECs); | — |
Countries
China
Contacts
Public ContactGao Xiumei
Tianjin University of Traditional Chinese Medicine (TCM)
Outcome results
None listed