Multiple uterine fibroids
Conditions
Interventions
Group A:None
Group B:Monthly injection of 3.75mg GnRHa for 6 months
Sponsors
Tongji Medical College Huazhong University of Science and Technology
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Clinical diagnosis of multiple uterine fibroids (imaging-confirmed); 2.Conservative surgical treatment with pathological diagnosis confirming uterine leiomyoma; 3.Postoperative ultrasound confirming no residual fibroids or fibroid size < 2 cm; 4.Age 18–45 years; 5.First-time treatment (no use of steroid hormones within 3 months prior to treatment); 6.No significant past medical history; 7.Ability to comply with follow-up and good adherence; 8.Signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Concurrent participation in other drug clinical trials; 2.Patients who are pregnant; 3.Patients with a history of cardiovascular or cerebrovascular accidents, hepatic or renal dysfunction, reproductive tract malformations, breast masses of undetermined nature, or other malignancies; 4.Patients who cannot tolerate surgery; 5.Patients with intolerance or allergy to the drug components.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The recurrence time and recurrence rate of uterine fibroids ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Health-related quality of life;Sex hormone test;anti-Müllerian hormone, AMH;CA125; | — |
Countries
China
Contacts
Public ContactWang Shixuan
Tongji Medical College Huazhong University of Science and Technology
Outcome results
None listed