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Efficacy and safety of indomethacin in the treatment of mild, moderate, severe acute pancreatitis: a single center, randomized, controlled clinical trial

Efficacy and safety of indomethacin in the treatment of mild, moderate, severe acute pancreatitis: a single center, randomized, controlled clinical trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-17012971
Enrollment
Unknown
Registered
2017-10-13
Start date
2017-10-08
Completion date
Unknown
Last updated
2017-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute pancreatitis

Interventions

treatment group:indomethacin

Sponsors

Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) Informed consent was previously diagnosed in patients with mild, moderate, severe acute pancreatitis. The diagnosis is in accordance with the criteria established by Gastroenterology Chinese Medical Association credits will Pancreatology group; 2) Patients aged 18 to 75 years when signing informed consent; 3) The subjects fully understand and comply with the requirements of the research program and sign the informed consent voluntarily; 4) All cases were obtained by the Medical Ethics Committee.

Exclusion criteria

Exclusion criteria: 1) The onset of treatment has been more than 48h; 2) Allergy to NSAIDs; 3) Active gastrointestinal bleeding; 4) Anticoagulants or antiplatelet agents were used two weeks before onset; 5) Severe liver dysfunction, renal dysfunction; 6) Active peptic ulcer and other disabled NSAIDs patients; 7) Pregnancy or lactation patients; 8) Severe cardiovascular and uncontrolled hypertension; 9) Mental disorders can not cooperate with the patient.

Design outcomes

Primary

MeasureTime frame
Total effective rate of treatment;

Secondary

MeasureTime frame
Severity of abdominal pain;thetime of symptom improvement;Diet opening time;

Countries

China

Contacts

Public ContactDong Wu

Peking Union Medical College Hospital

wudong061002@aliyun.com+86 18612671010

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026