LUNG CANCER
Conditions
Interventions
CONTROL GROUP:EGFR TKI
STUDY GROUP:ELEMMENE+EGFR TKI
Sponsors
HI CANCER CENTER, AFFILATED HOSPITAL OF HANGZHOU NORMAL UNIVERSITY
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Diagnosis as lung adenocarcinoma; 2. Aged=18; 3. KPS =70, or ECOG=2, estimated survival longer than 3 months; 4. Without major organ dysfunction. CBC and CX7 are normal. WBC>3.0×10^9/L, PLT>70×10^9/L, Hb>8g/dl, TB=2.5ULN, AST/ALT=2.5ULN (for liver metastasis=5ULN ); Cr=133umol/L; PT/APTT=1.5ULN; 5. Able to understand the study and voluntarily receive treatment and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patient has two or more primary cancer (if metachronous tumors, should be well controlled); 2. Receiving chemotherapy and radiotherapy; 3. Having used elemene in 1 month; 4. With serious disease, such as AIDS, or severe cardiovascular disease, liver disease, kidney disease, hematologic diseases, may affects the survival of the patient; 5. Mentally or legally disabled person; 6. Suspected or indeed a history of alcohol / drug abuse or, depending on the investigator's judgment, other complications such as decreased likelihood of entry or complication, such as frequent changes in the work environment, are likely to cause loss of visit; 7. Allergic to elemene; 8. Participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OBJECTIVE REMMISION RATE;PFS; | — |
Secondary
| Measure | Time frame |
|---|---|
| OVERALL SURVIVAL;SAFETY AND TOLERANCE;DISEASE CONTROL RATE;TCM SYMPTOMS; | — |
Countries
China
Contacts
Public ContactXIE TIAN
HI CANCER CENTER, AFFILATED HOSPITAL OF HANGZHOU NORMAL UNIVERSITY
Outcome results
None listed