Helicobacter pylori infection
Conditions
Interventions
Optimized bismuth plus triple therapy A:Optimized bismuth plus triple therapy A
Optimized bismuth plus triple therapy B:Optimized bismuth plus triple therapy B
Sponsors
Department of Gastroenterology, Peking University Third Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The patients with dyspepsia who are referred to our hospital for upper endoscopy; 2. HP RUT and W-S staining positive; 3. Never received treatment for H. pylori infection; 4. Aged 18 to 70 years; 5. Willing and available for participation this study
Exclusion criteria
Exclusion criteria: 1. Taking any drug which could influence the study results such as PPI, H2-receptor blockers, bismuth salts and antibiotics in the previous 4 weeks; 2. Gastrointestinal malignancy; 3. Zollinger-Ellison syndrome; 4. Previous gastric and esophageal surgeries; 5. Severe concomitant cardiovascular, respiratory, renal, hepatic, hematological, neurological, endocrine or psychiatric diseases; 6. History of allergy to any of the drugs used in the study; 7. Pregnancy or lactation; 8. Any other clinically significant medical condition that could increase risk of side effects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Compliance;Safety; | — |
Countries
China
Contacts
Public ContactLiya Zhou
Department of Gastroenterology, Peking University Third Hospital
Outcome results
None listed