procedural sedation and analgesia in plastic surgery
Conditions
Interventions
Group demedetomidine-remifentanil:Dexmedetomidine with target-controlled infusion of remifentanil
Group propofol-remifentanil:Propofol-remifentanil target-controlled infusion
Sponsors
Plastic Surgery Hospital, CAMS, PUMC
Eligibility
Sex/Gender
All
Age
18 Years to 59 Years
Inclusion criteria
Inclusion criteria: Aged 18-59 years old; ASA 1-2; scheduled to receive non-craniofacial plastic surgery under procedural sedation and analgesia; operation time > 30 minutes; informed consent signed.
Exclusion criteria
Exclusion criteria: operation time < 30 minutes; overstress; history of cardiovascular disease, respiratory disease, neuropsychopathy, and endocrine system disease, liver and kidney dysfunction; known or admitted alcohol or drug misuse; abnormality in airway, hearing, and intelligence, and those with communication difficulties; and those who refused to give informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood oxygen saturation;respiratory rate;manual airway intervention;incidence of hypoxemia;incidence of bradypnea or apnea; | — |
Secondary
| Measure | Time frame |
|---|---|
| BIS value;Observer's assessment of alertness/sedation scale;ETCO2;induction time;recovery time;blood pressure;heart rate;incidence of intraoperative pain ;patient satisfaction;surgeons satisfaction;anesthesiologists satisfaction;postoperative pain; | — |
Countries
China
Contacts
Public ContactYuhui Wang
Department of Anesthesiology, Plastic Surgery Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed