High Risk Non-Disabling Ischemic Cerebrovascular Disease
Conditions
Interventions
Two cohorts:take NBP versus without NBP
Sponsors
The affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. aged 18 to 75 years male and female; 2. Onset the stroke no more than 72 hours; 3. TIA patients that has a high risk of stroke (ABCD2 score on admission>=4) or minor stroke (admitted to hospital NIHSS<=3) and no thrombolytic therapy; 4. Obtained the signed the informed consent from patients or patients with legally authorized representatives.
Exclusion criteria
Exclusion criteria: 1) coma (NIHSS 1a awareness level item> 1 point of the patient); 2) moderate to severe stroke symptoms (NIHSS> 3 points); 3) pseudo-pulpal numbness with dysphagia; 4) craniocerebral CT findings of intracranial hemorrhagic disease: cerebral hemorrhage, ventricular hemorrhage, subarachnoid hemorrhage, subdural or epidural hematoma; 5) previous cerebral hemorrhage, subarachnoid hemorrhage, cerebral arteriovenous malformations or cerebral aneurysms, brain tumor history; 6) combined with severe heart, liver, kidney and other organs dysfunction; 7) pregnant or lactating women and pregnant throughout the trial period; 8) with mental symptoms unable to collaborate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total effective rate of treatment on day 90; | — |
Secondary
| Measure | Time frame |
|---|---|
| platelet microparticles level;The incidence of stroke;Congnitive ablilty; | — |
Countries
China
Contacts
Public ContactHuiting Zhang
The affiliated Hospital of Guangdong Medical University
Outcome results
None listed