Clinical safety and efficacy of dexmedetomidine alone for conscious sedation during ERCP:a randomized controlled trial

Clinical safety and efficacy of high dose dexmedetomidine alone for conscious sedation during ERCP:a randomized controlled trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-17012543

Enrollment

Unknown

Registered

2017-09-01

Start date

2017-09-01

Completion date

Unknown

Last updated

2017-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ERCP

Interventions

D:Dexmedetomidine sedation

P:propofol TCI

Eligibility

Sex/Gender

All

Age

45 Years to 85 Years

Inclusion criteria

Inclusion criteria: Aged 45-85 years old, need to do ERCP patients

Exclusion criteria

Exclusion criteria: 1. expected difficult airway; (neck movement limited, Mallampati 4, and chin distance 30; 5. gastroesophageal reflux disease; 6. sinus bradycardia, atrioventricular block and sick sinus syndrome. 7.ASA IV-V 8. coagulation abnormalities 9. alcohol dependence 10. long-term use of chronic illicit drugs 11. pregnancy

Design outcomes

Primary

Measure	Time frame
SpO2;RR;PCO2;Hypoxemia (SPO2< 90%), severe hypoxemia (SPO2 < 85%): frequency, duration;Airway manual intervention, events, and management;Manual intervention time / non manual intervention time;	—

Secondary

Measure	Time frame
RASS;BIS;Time required for induction;HR;MAP;The duration of operation;Eye opening time;Time to leave endoscopy center;Physician satisfaction;patient satisfaction;Drugs for special use (additional sufentanil and total propofol);	—

Countries

China

Contacts

Public ContactZhaoyang Xiao

The Second Hospital of Dalian Medical University

xiaozhaoy2012@163.com+86 17709873399

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026