Hip osteoarthritis/Necrosis of femoral head
Conditions
Interventions
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients following primary total hip arthroplasty due to osteoarthritis; (2) Patinets with preoperative platelet and coagulation function dysfunction; (3) Preoperative double lower limb venous color Doppler ultrasound was not abnormal; (4) voluntarily participated in clinical trials and signed informed consent, good compliance of patients.
Exclusion criteria
Exclusion criteria: (1) Patinets with history of venous thromboembolism, pulmonary embolism, cerebral infarction, coronary heart disease; (2) Patients with coagulation disorders; (3) Anticoagulant drugs are being used; (4) Administration of NSAID for less than 1 weeks; (5) TXA allergy; (6) Severe liver and renal insufficiency; (7) Patients with high risk of thrombosis, including atrial fibrillation, cardiac pacemaker, and stent implantation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total blood loss; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hb level;Hct;Hb drop;Intraoperative blood loss;Hidden blood loss;DVT & PE;Wound complications;Other adverse events; | — |
Countries
China
Contacts
Public ContactZhou Zongke
West China Hospital, Sichuan University
Outcome results
None listed