Rosacea
Conditions
Interventions
1:Hydroxychloroquine
two:Doxycycline
Sponsors
Central South University Xiangya Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. patients with severe erythema glaucoma dilatation and papular pustular rosacea (based on diagnostic criteria and scoring rules = 5 points); 2. voluntarily signed informed consent.
Exclusion criteria
Exclusion criteria: 1. age 65 years old; 2. pregnant and lactating women and the recent pregnancy planner; 3. accompanied by moderate to severe liver, kidney, lung or blood and other systemic diseases; 4. combined with nasal hypertrophy of hypertrophic rosacea patients; 5. within 3 months of oral administration of glucocorticoids, antibiotics or Victoria A acid and so on; 6. 1 month and outside with glucocorticoid ointment or tacrolimus (pimecrolimus) or laser and other treatment; pregnant and lactating women; accompanied by moderate to severe liver, kidney, lung or blood and other diseases; 7. Consolidate the facial manifestations of other facial skin diseases or other diseases; 8. To be expected to not adhere to follow-up patients; 9. Participated in any clinical trial in January; 10. people with mental disorders; 11. Allergy to chloroquine or hydroxychloroquine or allergy to tetracycline.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physical examination;vital signs;Blood routine;Urine routine;liver function;renal function;ANA;Fundus examination;Urine pregnancy test;Rose Acne Patient Facial Clinical Photo;Rose Acne Patient Face VISIA Photo;Rose Acne Patients Quality of Life Scale;Rose acne erythema score scale (patient self-assessment);Rose Acne Scoliosis Scale (Researcher Evaluation); | — |
Countries
China
Contacts
Public ContactHongfu Xie
Central South University Xiangya Hospital
Outcome results
None listed