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Effects of combination Ezetimibe and Rosuvastatin Versus Rosuvastatin Alone on pro-inflammation and endothelial function in Patients With ACS underging PCI

Effects of combination Ezetimibe and Rosuvastatin Versus Rosuvastatin Alone on pro-inflammation and endothelial function in Patients With ACS underging PCI

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-17012219
Enrollment
Unknown
Registered
2017-08-02
Start date
2017-08-01
Completion date
Unknown
Last updated
2017-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute coronary syndrome

Interventions

Ezetimibe +Rosuvastatin:Patients receiving Ezetimibe 10 mg/day and Rosuvastatin 10 mg/day.
Rosuvastatin:Patients receiving Rosuvastatin 10 mg/day

Sponsors

Department of Cardiology, Southwest Hospital, Third Military Medical University, Chongqing, China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18-80 years, male and female; 2. patients with unstable angina pectoris; 3. patients with non ST segment elevation myocardial infarction; 4. patients with ST segment elevation myocardial infarction

Exclusion criteria

Exclusion criteria: 1. Infectious diseases; 2. Malignant tumor; 3. Liver and kidney function obviously abnormal disease; 4. rheumatism immunity disease; 5. Hematological system diseases; 6. Intolerance or allergy to ezetimibe or rosuvastatin; 7. Pregnant or lactating women; 8. Not undergoing PCI treatment.

Design outcomes

Primary

MeasureTime frame
sPLA2-IIa;IL-1ß;VCAM-1;ICAM-1;

Countries

China

Contacts

Public ContactSong Zhiyuan

Department of Cardiology, Southwest Hospital, Third Military Medical University

zysong2010@126.com+86 13908327066

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026