atrial fibrillation
Conditions
Interventions
A:Rotor + CPVI
B:CPVI+ CFAEs
C:CPVI
Sponsors
Shanghai Chest Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years old; 2. paroxysmal symptomatic AF; 3. refractoriness to at least one antiarrhythmic drug; 4. left atrial diametrer = 45mm.
Exclusion criteria
Exclusion criteria: 1. With uncontrolled congestive heart failure; 2. Having significant valvular disease and/or prosthetic heart valve(s); 3. With myocardial infarction or stroke within 6 months of screening; 4. With Significant congenital heart disease; 5. Ejection fraction was <40% measured by echocardiography; 6. Allergic to contrast media; 7. Contraindication to warfarin or heparin; 8. Severe pulmonary disease e.g. restrictive pulmonary disease, chronic obstructive disease (COPD); 9. Left atrial (LA) thrombus measured by pre-procedure transesophageal echocardiography; 10. having any contraindication to right or left sided heart catheterization; 11. Poor general health; 15. Life expectancy less than 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of AF recurrence;Rate of atrial flutter or atrial tachycardia;Changes in the diameter of the left atrium and the left ventricular ejection fraction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of complications; | — |
Countries
China
Contacts
Public ContactXu Liu
Shanghai Chest Hospital
Outcome results
None listed