Influence of pain nalbuphine preemptive analgesia in laparoscopic cholecystectomy patients and postoperative serum inflammatory factors

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-17011974

Enrollment

Unknown

Registered

2017-07-13

Start date

2017-08-01

Completion date

Unknown

Last updated

2017-07-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gallbladder stone or cholecystitis

Interventions

Nalbuphine preemptive analgesia group (group A)

nalbuphine postoperative analgesia group (group B)

control group (group C):Different administration time of nalbuphine

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Aged from 18 to 65 years old, BMI18 ~ 30kg/m2; ASA I-II; no preoperative history of chronic disease, no liver and kidney dysfunction; two weeks without acute cholecystitis history; two weeks without the application of narcotic analgesics in history; voluntary informed consent

Exclusion criteria

Exclusion criteria: Unconsciousness or cognitive dysfunction; alcohol and drug abuse history; underweight or overweight (standard weight±20%); the operation time is less than 30min or more than 90min; halfway away abdomen; history of motion sickness

Design outcomes

Primary

Measure	Time frame
VAS score;interleukin-6;substance P;interleukin-10;	—

Countries

China

Contacts

Public ContactXizhe Zhang

Department of Anesthesiology, Chifeng Hospital

zhangxizhe1965@sina.com+86 13500660020

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026