Osteoarthritis of the knee
Conditions
Interventions
Sponsors
The Third Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. according to the diagnostic criteria of knee osteoarthritis, clinical diagnosis of osteoarthritis of the knee; 2. Imaging findings of the knee indicate joint effusion and / or synovitis; 3. 40 years of age or older, male or female; 4. agree to participate in the clinical trial and sign the informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. Kellgren-Lawrecne, knee osteoarthritis, X-ray classification, grade 4 patients; 2. osteoarthritis of the knee caused by rheumatoid arthritis, traumatic arthritis, gouty arthritis, tuberculosis, or allergies; 3. infection, fracture, dislocation, ligament rupture, meniscus injury, pigmented villonodular synovitis, hemophilia arthritis and so on, can cause joint pain, swelling and dysfunction of the disease; 4. combined with heart, liver, kidney, hematopoietic system and other important organs and systems, serious primary diseases, ALT, AST > 1.5 times the normal value, Cr > 133 mu mol/L; 5. joint pain degree evaluation of any VAS score more than 7 points; 6. have a history of drug abuse, alcohol abuse or mental illness; 7. pregnant women, lactating women and the recent fertility program; 8. allergic to the known components of this test drug and allergic constitution; 9. participated in other clinical trials in the first 3 months; 10. the researchers found it inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kellgren-Lawrence;womac; | — |
Countries
China
Contacts
Public ContactBaicheng Chen
The Third Hospital of Hebei Medical University
Outcome results
None listed