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Effects of different frequencies of repetitive transcranial magnetic stimulation for cognitive impairment after stroke and the mechanism of neural reorganization

Effects of different frequencies of repetitive transcranial magnetic stimulation for cognitive impairment after stroke and the mechanism of neural reorganization

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-17011908
Enrollment
Unknown
Registered
2017-07-08
Start date
2017-07-07
Completion date
Unknown
Last updated
2017-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-stroke cognitive impairment

Interventions

10hz stimulation group:rTMS
1hz stimulation group:rTMS
sham stimulation group:sham rTMS

Sponsors

The Third Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Stroke patients in accordance with the diagnostic criteria established by the fourth national cerebrovascular disease academic conference in 1995; 2. first-ever stroke; 3. obvious cognitive impairments (MMSE=10-24,MoCA<26); 4. stable vital signs, no progression of neurological symptoms; 5. no severe aphasia and able of accomplishing cognitive tests; 6. normal cognitive functions before stroke; 7. aged 30-75 years; 8. able of tolerating mri scan; 9. voluntary participation and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Non-first stroke; 2. complete left prefrontal cortex injury; 3. transcranial surgery or skull defect; 4. metal or cardiac pacemaker implants; 5. history of brain tumor, brain trauma, seizures and risks of seizures; 6. cognitive function recession before stroke; 7. any neuropsychiatric comorbidity and affective disorder that could influence the test outcomes; 8. any other factors that could affect cognitive assessments and treatments.

Design outcomes

Primary

MeasureTime frame
MoCA;

Secondary

MeasureTime frame
MMSE;stroop test;RBMT;Digit span test;MBI;

Countries

China

Contacts

Public ContactHu Xiquan

The Third Affiliated Hospital of Sun Yat-sen University

xiquhu@hotmail.com+86 18922102910

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 17, 2026