Bone Loss or Osteoporosis in Female Perimenopausal Syndrome
Conditions
Interventions
Control group:Blank placebo
Calcium group:Calcium 250mg 2 / d
Soy isoflavones group:Soy isoflavones 30mg 2?/d
Soybean isoflavones combined with calcium:Calcium 250mg 2 / d + Soy isoflavones 30mg 2?/d
Sponsors
Department of Nutrition, Chinese PLA General Hospital
Eligibility
Sex/Gender
Female
Age
40 Years to 55 Years
Inclusion criteria
Inclusion criteria: (1) Aged 40-55 years old Female; (2) In perimenopausal period; (3) Diagnosed as perimenopausal syndrome; (4) Bone mineral density measurement to determine bone loss or osteoporosis; (5) Can follow up, compliance is good; (6) Voluntarily participate in this study, accept a variety of testing and investigation.
Exclusion criteria
Exclusion criteria: (1) To exclude the congenital or acquired immunodeficiency disease; (2) To exclude acute and chronic liver and kidney disease, endocrine and other diseases and taking hormones and other drugs; (3) To exclude the presence or family history of breast cancer and uterine cancer in the crowd; (4) Excluding those who have used vitamins or other health supplements within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone density measurement;Determination of serum indicators;Comprehensive assessment of menopause;Determination of urinary Eq and detection of fecal intestinal flora; | — |
Secondary
| Measure | Time frame |
|---|---|
| General investigation;Fatigue rating;Anxiety, depression score; | — |
Countries
China
Contacts
Public ContactLiu Yinghua
Chinese PLA General Hospital
Outcome results
None listed