burning mouth syndrome
Conditions
Interventions
The control group:Oryzanol Tablets, oral taken, 10mg/ time, 3 times / day
The experimental group:Oryzanol Tablets, oral taken, 10mg/ time, 3 times/day
vitamin B2 tablets, oral taken, 10mg/time, 3 times/day
vitamin E pills, oral taken, 100mg/ time, 1 times/day, taking 1 months as a course. On the basis of the triple drug therapy, the experimental group was treated with biofeedback
vitamin B2 tablets, oral taken, 10mg/ time, 3 times / day
vitamin E pills, oral taken, 100mg/ time, 1 times / day, taking 1 months as a course.
Sponsors
Sichuan University, West China Hospital of Stomatology
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) People aged 18-65 years; (2) Through the detailed inquiry of the medical history, the symptoms and signs do not meet the clinical characteristics can be diagnosed as BMS, >6 months of history; (3) There is no revision local irritant of burning pain in the mouth; (4) The whole blood chart, blood sugar, liver and kidney function, routine urine test, abdominal ultrasound examination, chest X-ray examination and other basic physical examination items were normal; (5) In order to improve sleep occasionally take sleeping or hypnotic drugs; (6) Volunteer to participate in this experiment and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) There are local irritation factors which can cause burning pain in the mouth (including bad restoration, sharp teeth tip, tooth ridge, complete denture, etc.); (2) Suffer from other serious oral mucosal diseases (including oral candidiasis, oral lichen planus, all kinds of oral ulcers, bullous diseases, etc.); (3) Patients with serious systemic diseases (heart disease, kidney disease, hypertension, diabetes mellitus, etc.); (4)Patients who received routine medication because of neurological dysfunction or mental disorders (diagnosed by specialist outpatient clinic of 3A Hospitals); (5) Scalp infections may affect electrode installers; (6) Patients with organic lesions in the brain (such as brain tumors, cerebral hemorrhage, etc.); (7) Pregnant women or lactating women; (8) Low cognitive level, unable to correctly understand and fill out questionnaires; (9) Unable to comply with the doctor's instructions or unable to return the patient on time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain index;Effective sleep time;Anxiety/Depression index; | — |
Countries
China
Contacts
Public ContactZhou Hongmei
West China Hospital of Stomatology, Sichuan University
Outcome results
None listed