periodontitis
Conditions
Interventions
control:nano carbonate apatite free toothpaste
test group:nano carbonate apatite toothpaste
Sponsors
The Second Affiliated Hospital of Zhejiang University School of Medcine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. aged 18 to 70 years; 2. no systemic disease; 3. with a diagnosis of moderate to severe periodontitis who need to be treated with non-surgical periodontal treatment (scaling and root planing) in one session; 4. satisfactory dental restorations and no caries in all of the teeth; 5. pre-existing dentine hypersensitivity in at least two teeth(VAS between 3.0 to 8.0)and can be diagnosed by visual or probing inspection; 6. not using agents to treat hypersensitivity in the past 6 months
Exclusion criteria
Exclusion criteria: 1. smoking; 2. subjects with gross oral pathology, chronic disease, extremely advanced periodontal disease, periodontal treatment within the last 12 months; 3. hypersensitive teeth with mobility greater than one; 4. teeth with extensive (implicating equal or more than 2/3 of the crown) and/or defective restorations, suspected pulpitis, caries or cracked enamel; 5. subjects with removable appliances, such as removable partial dentures or orthodontic retainers; 6. subjects taking anticonvulsants, antihistamines, antidepressants, sedatives, tranquilizers, anti-inflammatory drugs or daily analgesics within 1 month prior to enrollment to the study or if they started taking them during the course of the study; 7. pregnant or lactating women; 8. subjects who are participating in any other clinical study or who have participated in a desensitizing toothpaste study or who used a desensitizing toothpaste within the last 3 months, or had a dental prophylaxis within 2-weeks prior to the projected date of the screening visit; 9. subjects with a history of allergy to the test products, or allergies to oral care/personal care consumer products or their ingredients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Schiff Cold Air Sensitivity; | — |
Countries
China
Contacts
Public ContactDing Peihui
The Second Affiliated Hospital of Zhejiang University School of Medcine
Outcome results
None listed