hepatocirrhosis
Conditions
Interventions
hepatocirrhosis with sufentanil group:sufentanil 0.2-0.3ng/ml TCI
hepatocirrhosis with remifentanil group:remifentanil 2-4ng/ml TCI
non-cirrhosis with sufentanil group:sufentanil 0.2-0.3ng/ml TCI
non-cirrhosis with remifentanil group:remifentanil 2-4ng/ml TCI
Sponsors
Department of Anaesthesiology, Southwest Hospital, Third Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. patients with normal liver function; aged 18-70; both male and female; abdominal surgery;voluntarily signed the consent form and participate in the study informed consent; 2. hepatocirrhosis patients with Child-Pugh A; aged 18-70; both male and female;abdominal surgery; voluntarily signed the consent form and participate in the study informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe heart pulmonary or renal diseases pre-operation.Including cardiac failure, severe cardiac arrhythmia affecting circulation, severe COPD; 2. A previous history of alcohol abuse, substance abuse and surgical anesthesia; 3. psychotic patients; 4. Participating in other clinical trials; 5. Patient with other reasons do not fit the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Von Frey thresholds;Oxyhemoglobin desaturation; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS;trigger frequency;opioid consumption;PO2;PCO2;Recovery time in PACU; | — |
Countries
China
Contacts
Public ContactBin Yi
Department of Anaesthesiology, Southwest Hospital, Third Military Medical University
Outcome results
None listed