A multicentre randomized controlled study of the efficacy and comfort of propofol combined with nalbuphine and fentanyl in patients undergoing painless colonoscopy

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-17011516

Enrollment

Unknown

Registered

2017-05-27

Start date

2017-06-01

Completion date

Unknown

Last updated

2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Digestive diseases

Interventions

experimental group:nalbuphine

control group:fentanyl

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Intended to perform painless colonoscopy; (2) aged 18-65 years; (3) BMI (Body Mass Index) 18.5~30 kg/m2; (4) ASA I-III; (5) the duration time of gastroscopy <30min.

Exclusion criteria

Exclusion criteria: (1) history of a serious heart, brain, lung, liver, kidney and metabolic disease; (2) History of abnormal anesthesia recovery; (3) ECG:Heart rate(HR)180/110 mmHg and/or diastolic blood pressure (DBP) > 110 mmHg, or BP < 90/60 mmHg; (6) neuromuscular disease or mental illness; (7) Hemoglobin less than 90g/L; (8) Suspected abuse of narcotic analgesics or sedatives; (9) possible or happened difficult airway; (10) allergy to emulsion or opioid; (11) Patients do not fit or can not communicate.

Design outcomes

Primary

Measure	Time frame
Patient satisfaction;	—

Secondary

Measure	Time frame
blood pressure;Respiratory rate;heart rate;BPS-NI score;Ramsay score;	—

Countries

China

Contacts

Public ContactMa Zhengliang

Nanjing Drum Tower Hospital

13611586781@163.com+86 13611586781

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026