localized chronic eczema
Conditions
Interventions
Compound Glycyrrhizin Capsules:take Compound Glycyrrhizin Capsules 75mg, 3 times a day
apply Mometasone Furoate onitment once a day
placebo capsule group:take placebo Capsules 75mg, 3 times a day
Sponsors
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. aged from 18-80 years male and female; 2. Clinically Diagnosed localized chronic eczema, Skin involvement for 5% to 15% of body surface areapatients; 3. The disease has no obvious cause; 4. Participant fully understands the content of the clinical trial, is willing to attend the research voluntary andsign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. eczema infected with the bacteria, viruses, or fungi; 2. during gestational and lactation period; 3. patients who are allergic to any ingredient of the drug to be studied; 4. Have severe hepatic disease, kidney disease, hematological system diseases, autoimmune disease,chronic severe infectious disease,diabetes, mental illness, drug addiction, alcoholism; 5. have a history of malignancy or any severe or uncontrolled systemic disease; 6. apply corticosteroids cream within 2 weeks;have taken systemic corticosteroids or other systemic immune inhibitors (e.g. Tripterygium wilfordii et al.) within 4 weeks; 7. rash on face, skin folds such as anus, vulva; 8. Skin lesions with a total area of more than 15% of the body surface area or less than 25 cm2; 9. other reasons that researchers think that should not be selected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EASI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pruritus;adverse event;Symptom score changing; | — |
Countries
China
Contacts
Public ContactLinfeng Li
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed