Effect of dexmethasone addition on rebound pain after single shot nerve block with ropivacaine

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-17011365

Enrollment

Unknown

Registered

2017-05-11

Start date

2017-01-02

Completion date

Unknown

Last updated

2017-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pain

Interventions

test group:ultrasound guided nerve block with 0.375% ropivacaine with addition of 8mg dexamethasone

control group:ultrasound guided nerve block with 0.375% ropivacaine 30ml

Eligibility

Sex/Gender

All

Age

19 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients receive open reduction and internal fixation of upper limb fracture under single shot peripheral nerve block combined with sedation; 2. Aged>18yr; 3. Inform consent is signed.

Exclusion criteria

Exclusion criteria: 1. Patients refuse; 2. Patients with peripheral nerve damage or lesion who is contraindicated to nerve block; 3. Chronic analgesics use; 4. Massive compound trauma; 5. Pregnant women.

Design outcomes

Primary

Measure	Time frame
breakthrough pain after surgery;total consumption of morphine, timing of bolus, effective/uneffective bolus, timing of salvage bolus;	—

Secondary

Measure	Time frame
sleep quality during the night of surgery day and POD1;	—

Countries

China

Contacts

Public ContactXiaoguang Zhang

Zhongshan Hospital, Fudan University

zhangxg@fudan.edu.cn+86 13641995733

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 16, 2026