intertrochanteric fracture
Conditions
Interventions
intravenous tranexamic acid:10 mg kg of i.v. tranexamic acid before surgery
Sponsors
Clinical Medical College of Yangzhou University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Adults aged 65 years and more; 2. intertrochanteric fracture; 3. Patients treated surgically with PFNA.
Exclusion criteria
Exclusion criteria: (1) Open fracture; (2) Combined with other fractures; (3) Preoperative hemoglobin less than 10g/L, the platelet count is less than 100 * 10^9/L; (4) History of DVT or pulmonary embolus; (5) Use of any anticoagulant at the time of admission; (6) Abnormal blood coagulation before surgery, serious liver/renal dysfunction; (7) Documented allergy to TXA; (8) Complicated with mental disorders unable to cooperate with the treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total blood loss;intraoperative blood loss;haemoglobin concentration on first post-operative day;Postoperative hemoglobin decreased maximum;the rate of transfusion;the rate of vascular events; | — |
Secondary
| Measure | Time frame |
|---|---|
| changes of blood coagulation index;Changes of fibrinolysis index;the rate of wound infection;Duration of surgery;Length of hospital stay; | — |
Countries
China
Contacts
Public ContactHe Jinshan
Clinical Medical College of Yangzhou University
Outcome results
None listed